RESUMO
Ten healthy volunteers were administered orally 0.04ml of Chelidonium majus 6c t.d.s. for 21 days. Seven healthy volunteers were kept as controls and administered orally 0.04ml. of 90percent ethanol t.d.s. The trial was single blind. Fasting venous samples were collected before and after the trial. Serum samples were analysed for total bilirubin, albumin, globulin, total cholesterol, prothrombin time and GPT. Serum globulins registered an increase of 58percent, while the other parameters showed no changes
Assuntos
Humanos , Masculino , Feminino , 60592/farmacologia , Fígado , Soroglobulinas , Ensaios Clínicos como AssuntoRESUMO
Crude venom (4 mg/kg) of scorpion (B. tamulus) was given in saline to anaesthetized dogs and rabbits. It produced a reduction in gastric H+ ion concentration in dogs with acute myocarditis. Simultaneously an increase in circulating amylase and lipase level was also observed. However 60% venom poisoned rabbits showed an elevated lipase level without a parallel increase in amylase. It is suggested that the venom acts directly on exocrine pancreas to cause acute pancreatitis.